Naco, a Census-Designated Place located in Cochise County, Arizona, United States had a recorded population of 1,046 during the 2010 census. It's located directly across the United States–Mexico border from its sister city Naco, Sonora. The Naco port of entry is open 24 hours per day.The present-day unincorporated town of Naco, Arizona, was established in the early 20th century. The area was originally settled by the Nahua and Opata Indians. Naco means "nopal cactus" in the Opata language. The U.S. Congress officially established Naco as a Port of Entry on June 28, 1902.